Expression, Characterisation and Mutagenesis of the Aspartic Proteinase from Equine Infectious Anaemia Virus
نویسندگان
چکیده
منابع مشابه
Equine Infectious Anaemia
Equine infectious anaemia (EIA) is a persistent viral infection of equids. The causative agent, EIA virus (EIAV) is a lentivirus in the family Retroviridae, subfamily Orthoretrovirinae. Other members of the genus Lentivirus include: bovine immunodeficiency virus; caprine arthritis encephalitis virus; feline immunodeficiency virus; human immunodeficiency virus 1; human immunodeficiency virus 2; ...
متن کاملExpression of functional protease and subviral particles by vaccinia virus containing equine infectious anaemia virus gag and 5' pol genes.
Cells infected with vaccinia viruses expressing the equine infectious anaemia virus (EIAV) gag gene (VGag) or gag plus the 5' pol encoding protease (VGag/PR) were evaluated with monoclonal antibody to a p26 capsid protein linear epitope (QEISKFLTD). Both recombinant viruses expressed Gag precursor protein (55K) whereas only VGag/PR expressed a detectable Gag-Pol fusion protein (82K) with a func...
متن کاملFreedom from equine infectious anaemia virus infection in Spanish Purebred horses
INTRODUCTION No cases of equine infectious anaemia (EIA) have been reported in Spain since 1983. Factors that could increase the risk of reintroducing equine infectious anaemia virus (EIAV) into Spain include the recent occurrence of the disease in Europe and the absence of compulsory serological testing before importation into Spain. AIMS AND OBJECTIVES Given the importance of the Spanish Pu...
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ژورنال
عنوان ژورنال: European Journal of Biochemistry
سال: 1996
ISSN: 0014-2956,1432-1033
DOI: 10.1111/j.1432-1033.1996.00664.x